Concept information
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Intracellular Signaling Peptides and Proteins
Phosphatidylinositol 3-Kinases
Phosphatidylinositol 3-Kinase
Class I Phosphatidylinositol 3-Kinases
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Intracellular Signaling Peptides and Proteins
Phosphatidylinositol 3-Kinases
Phosphatidylinositol 3-Kinase
Class I Phosphatidylinositol 3-Kinases
...
Phosphotransferases (Alcohol Group Acceptor)
Phosphatidylinositol 3-Kinases
Phosphatidylinositol 3-Kinase
Class I Phosphatidylinositol 3-Kinases
...
Intracellular Signaling Peptides and Proteins
Phosphatidylinositol 3-Kinases
Phosphatidylinositol-4-Phosphate 3-Kinase
Class I Phosphatidylinositol 3-Kinases
Preferred term
Class Ia Phosphatidylinositol 3-Kinase
Type
-
mesh:Descriptor
Definition
- A phosphatidylinositol 3-kinase subclass that includes enzymes formed through the heterodimerization of a p110 catalytic and a p85, p55, or p50 regulatory subunit. This subclass of enzymes is a downstream target of TYROSINE KINASE RECEPTORS and G PROTEIN-COUPLED RECEPTORS. A 55kDa variant protein resulting from alternatively-splicing of the phosphoinositide-3-Kinase, regulatory subunit 1mRNA. A 50kDa variant protein resulting from alternatively-splicing of the phosphoinositide-3-Kinase, regulatory subunit 1mRNA.
Broader concept
Entry terms
- Class Ia Phosphatidylinositol 3-Kinases
- Phosphatidylinositol 3-Kinase, Class Ia
Allowable Qualifier(s)
- administration & dosage (Qualifier)
- adverse effects (Qualifier)
- analysis (Qualifier)
- biosynthesis (Qualifier)
- blood (Qualifier)
- cerebrospinal fluid (Qualifier)
- chemical synthesis (Qualifier)
- chemistry (Qualifier)
- classification (Qualifier)
- deficiency (Qualifier)
- drug effects (Qualifier)
- economics (Qualifier)
- genetics (Qualifier)
- history (Qualifier)
- immunology (Qualifier)
- isolation & purification (Qualifier)
- metabolism (Qualifier)
- pharmacokinetics (Qualifier)
- pharmacology (Qualifier)
- physiology (Qualifier)
- poisoning (Qualifier)
- radiation effects (Qualifier)
- standards (Qualifier)
- supply & distribution (Qualifier)
- therapeutic use (Qualifier)
- toxicity (Qualifier)
- ultrastructure (Qualifier)
- urine (Qualifier)
In other languages
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French
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PI 3-kinase de classe Ia
URI
http://data.loterre.fr/ark:/67375/JVR-P7S5W0QC-S
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