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Biological Factors > Intercellular Signaling Peptides and Proteins > Cytokines > Transforming Growth Factor beta > Transforming Growth Factor beta1
... > Amino Acids, Peptides, and Proteins > Peptides > Intercellular Signaling Peptides and Proteins > Cytokines > Transforming Growth Factor beta > Transforming Growth Factor beta1
... > Amino Acids, Peptides, and Proteins > Proteins > Intercellular Signaling Peptides and Proteins > Cytokines > Transforming Growth Factor beta > Transforming Growth Factor beta1
Biological Factors > Intercellular Signaling Peptides and Proteins > TGF-beta Superfamily Proteins > Transforming Growth Factor beta > Transforming Growth Factor beta1
... > Amino Acids, Peptides, and Proteins > Peptides > Intercellular Signaling Peptides and Proteins > TGF-beta Superfamily Proteins > Transforming Growth Factor beta > Transforming Growth Factor beta1
... > Amino Acids, Peptides, and Proteins > Proteins > Intercellular Signaling Peptides and Proteins > TGF-beta Superfamily Proteins > Transforming Growth Factor beta > Transforming Growth Factor beta1

Preferred term

Transforming Growth Factor beta1  

Type

  • mesh:Descriptor

Definition

  • A subtype of transforming growth factor beta that is synthesized by a wide variety of cells. It is synthesized as a precursor molecule that is cleaved to form mature TGF-beta 1 and TGF-beta1 latency-associated peptide. The association of the cleavage products results in the formation a latent protein which must be activated to bind its receptor. Defects in the gene that encodes TGF-beta1 are the cause of CAMURATI-ENGELMANN SYNDROME.

Broader concept

Entry terms

  • TGF-beta-1
  • TGF-beta1
  • Transforming Growth Factor-beta1
  • Transforming Growth Factor beta I

Allowable Qualifier(s)

In other languages

URI

http://data.loterre.fr/ark:/67375/JVR-PCPKLTRW-C

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RDF/XML TURTLE JSON-LD Created 7/5/06, last modified 2/21/20