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Amino Acids, Peptides, and Proteins > Proteins > Protein Precursors > Progranulins > Granulins
Amino Acids, Peptides, and Proteins > Peptides > Peptide Hormones > Progranulins > Granulins
... > Chemical Actions and Uses > Pharmacologic Actions > Physiological Effects of Drugs > Hormones, Hormone Substitutes, and Hormone Antagonists > Hormones > Peptide Hormones > Progranulins > Granulins
Biological Factors > Intercellular Signaling Peptides and Proteins > Progranulins > Granulins
Amino Acids, Peptides, and Proteins > Peptides > Intercellular Signaling Peptides and Proteins > Progranulins > Granulins
Amino Acids, Peptides, and Proteins > Proteins > Intercellular Signaling Peptides and Proteins > Progranulins > Granulins

Preferred term

Granulins  

Type

  • mesh:Descriptor

Definition

  • Small, cysteine-rich peptides generated by the proteolytic cleavage of progranulin. Granulin peptides are each composed of a granulin-motif, while paragranulin is composed of a half-granulin motif. The mammalian granulins are named granulin 1-7 for their sequence order in the progranulin propeptide, and are alternately named granulin G, F, B, A, C, D, and E; or epithelin 7, 6, 2, 1, 3, 4, and 5, i.e. granulin 1 aka granulin G aka epithelin 7, etc. Granulin from the fifth granulin repeat of the proteolytically processed mammalian progranulin protein. It is also called granulin C or epithelin 3. Granulin from the seventh granulin repeat of the proteolytically processed mammalian progranulin protein. It is also called granulin E or epithelin 5. Granulin from the sixth granulin repeat of the proteolytically processed mammalian progranulin protein. It is also called granulin D or epithelin 4. Granulin from the fourth granulin repeat of the proteolytically processed mammalian progranulin protein. It is also called granulin A or epithelin 1. Granulin from the first granulin repeat of the proteolytically processed mammalian progranulin protein . It is also called Granulin G. Granulin from the second granulin repeat of the proteolytically processed mammalian progranulin protein. It is also called granulin F. Granulin from the third granulin repeat of the proteolytically processed mammalian progranulin protein . It is also called Granulin B. A granulin composed of the half granulin repeat.

Broader concept

Entry terms

  • 148708-92-3
  • Epithelin
  • Epithelins
  • Granulin
  • Granulin Peptides

Allowable Qualifier(s)

In other languages

  • Granulines

    French

  • 148708-92-3
  • Épithélines
  • Peptides de granuline

URI

http://data.loterre.fr/ark:/67375/JVR-PD7S7VH5-L

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