Concept information
Preferred term
Nicorandil
Type
-
mesh:Descriptor
Definition
- A derivative of the NIACINAMIDE that is structurally combined with an organic nitrate. It is a potassium-channel opener that causes vasodilatation of arterioles and large coronary arteries. Its nitrate-like properties produce venous vasodilation through stimulation of guanylate cyclase.
Broader concept
Entry terms
- 260456HAM0
- 2-Nicotinamidethyl Nitrate
- 2-Nicotinamidoethyl Nitrate
- 3-Pyridinecarboxamide, N-(2-(Nitroxy)ethyl)-
- 65141-46-0 (Nicorandil)
Allowable Qualifier(s)
- administration & dosage (Qualifier)
- adverse effects (Qualifier)
- agonists (Qualifier)
- analogs & derivatives (Qualifier)
- analysis (Qualifier)
- antagonists & inhibitors (Qualifier)
- blood (Qualifier)
- cerebrospinal fluid (Qualifier)
- chemical synthesis (Qualifier)
- chemistry (Qualifier)
- classification (Qualifier)
- economics (Qualifier)
- history (Qualifier)
- immunology (Qualifier)
- isolation & purification (Qualifier)
- metabolism (Qualifier)
- pharmacokinetics (Qualifier)
- pharmacology (Qualifier)
- poisoning (Qualifier)
- radiation effects (Qualifier)
- standards (Qualifier)
- supply & distribution (Qualifier)
- therapeutic use (Qualifier)
- toxicity (Qualifier)
- urine (Qualifier)
Pharmacological Action(s)
In other languages
-
French
-
260456HAM0
-
3-Pyridinecarboxamide, N-(2-(Nitroxy)ethyl)-
-
65141-46-0 (Nicorandil)
URI
http://data.loterre.fr/ark:/67375/JVR-PFB8MJLD-D
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