Concept information
Preferred term
Somatostatin
Type
-
mesh:Descriptor
Definition
- A 14-amino acid peptide named for its ability to inhibit pituitary GROWTH HORMONE release, also called somatotropin release-inhibiting factor. It is expressed in the central and peripheral nervous systems, the gut, and other organs. SRIF can also inhibit the release of THYROID-STIMULATING HORMONE; PROLACTIN; INSULIN; and GLUCAGON besides acting as a neurotransmitter and neuromodulator. In a number of species including humans, there is an additional form of somatostatin, SRIF-28 with a 14-amino acid extension at the N-terminal.
Broader concept
Narrower concepts
Entry terms
- 51110-01-1
- Cyclic Somatostatin
- Somatostatin-14
- Somatostatin, Cyclic
- Somatotropin Release-Inhibiting Factor
- Somatotropin Release-Inhibiting Hormone
- SRIH-14
Allowable Qualifier(s)
- administration & dosage (Qualifier)
- adverse effects (Qualifier)
- agonists (Qualifier)
- analogs & derivatives (Qualifier)
- analysis (Qualifier)
- antagonists & inhibitors (Qualifier)
- biosynthesis (Qualifier)
- blood (Qualifier)
- cerebrospinal fluid (Qualifier)
- chemical synthesis (Qualifier)
- chemistry (Qualifier)
- classification (Qualifier)
- deficiency (Qualifier)
- drug effects (Qualifier)
- economics (Qualifier)
- genetics (Qualifier)
- history (Qualifier)
- immunology (Qualifier)
- isolation & purification (Qualifier)
- metabolism (Qualifier)
- pharmacokinetics (Qualifier)
- pharmacology (Qualifier)
- physiology (Qualifier)
- poisoning (Qualifier)
- radiation effects (Qualifier)
- standards (Qualifier)
- supply & distribution (Qualifier)
- therapeutic use (Qualifier)
- toxicity (Qualifier)
- urine (Qualifier)
Pharmacological Action(s)
In other languages
-
French
-
51110-01-1
-
Facteur inhibant la libération de la somatotrophine
-
Facteur inhibant la libération de la somatotropine
-
Hormone inhibant la libération de la somatotrophine
-
Hormone inhibant la libération de la somatotropine
-
Somatostatine 14
-
Somatostatine cyclique
-
Somatostatine-14
-
SRIF-14
URI
http://data.loterre.fr/ark:/67375/JVR-PFHT2LB7-J
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