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Concept information

Preferred term

Somatostatin  

Type

  • mesh:Descriptor

Definition

  • A 14-amino acid peptide named for its ability to inhibit pituitary GROWTH HORMONE release, also called somatotropin release-inhibiting factor. It is expressed in the central and peripheral nervous systems, the gut, and other organs. SRIF can also inhibit the release of THYROID-STIMULATING HORMONE; PROLACTIN; INSULIN; and GLUCAGON besides acting as a neurotransmitter and neuromodulator. In a number of species including humans, there is an additional form of somatostatin, SRIF-28 with a 14-amino acid extension at the N-terminal.

Narrower concepts

Entry terms

  • 51110-01-1
  • Cyclic Somatostatin
  • Somatostatin-14
  • Somatostatin, Cyclic
  • Somatotropin Release-Inhibiting Factor
  • Somatotropin Release-Inhibiting Hormone
  • SRIH-14

Pharmacological Action(s)

In other languages

  • French

  • 51110-01-1
  • Facteur inhibant la libération de la somatotrophine
  • Facteur inhibant la libération de la somatotropine
  • Hormone inhibant la libération de la somatotrophine
  • Hormone inhibant la libération de la somatotropine
  • Somatostatine 14
  • Somatostatine cyclique
  • Somatostatine-14
  • SRIF-14

URI

http://data.loterre.fr/ark:/67375/JVR-PFHT2LB7-J

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RDF/XML TURTLE JSON-LD Created 11/11/74, last modified 11/24/15