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... > Amino Acids, Peptides, and Proteins > Proteins > Glycoproteins > Membrane Glycoproteins > Cell Adhesion Molecules > CD11 Antigens > Lymphocyte Function-Associated Antigen-1
... > Carbohydrates > Glycoconjugates > Glycoproteins > Membrane Glycoproteins > Cell Adhesion Molecules > CD11 Antigens > Lymphocyte Function-Associated Antigen-1
... > Amino Acids, Peptides, and Proteins > Proteins > Membrane Proteins > Membrane Glycoproteins > Cell Adhesion Molecules > CD11 Antigens > Lymphocyte Function-Associated Antigen-1
... > Biological Factors > Antigens > Antigens, Surface > Cell Adhesion Molecules > CD11 Antigens > Lymphocyte Function-Associated Antigen-1
... > Amino Acids, Peptides, and Proteins > Proteins > Membrane Proteins > Receptors, Cell Surface > Receptors, Immunologic > Receptors, Lymphocyte Homing > Lymphocyte Function-Associated Antigen-1
... > Amino Acids, Peptides, and Proteins > Proteins > Glycoproteins > Membrane Glycoproteins > Cell Adhesion Molecules > Receptors, Lymphocyte Homing > Lymphocyte Function-Associated Antigen-1
... > Carbohydrates > Glycoconjugates > Glycoproteins > Membrane Glycoproteins > Cell Adhesion Molecules > Receptors, Lymphocyte Homing > Lymphocyte Function-Associated Antigen-1
... > Amino Acids, Peptides, and Proteins > Proteins > Membrane Proteins > Membrane Glycoproteins > Cell Adhesion Molecules > Receptors, Lymphocyte Homing > Lymphocyte Function-Associated Antigen-1
... > Biological Factors > Antigens > Antigens, Surface > Cell Adhesion Molecules > Receptors, Lymphocyte Homing > Lymphocyte Function-Associated Antigen-1
... > Amino Acids, Peptides, and Proteins > Proteins > Membrane Proteins > Receptors, Cell Surface > Receptors, Immunologic > Integrins > Receptors, Leukocyte-Adhesion > Lymphocyte Function-Associated Antigen-1

Preferred term

Lymphocyte Function-Associated Antigen-1  

Type

  • mesh:Descriptor

Definition

  • An integrin heterodimer widely expressed on cells of hematopoietic origin. CD11A ANTIGEN comprises the alpha chain and the CD18 antigen (CD18 ANTIGENS) the beta chain. Lymphocyte function-associated antigen-1 is a major receptor of T-CELLS; B-CELLS; and GRANULOCYTES. It mediates the leukocyte adhesion reactions underlying cytolytic conjugate formation, helper T-cell interactions, and antibody-dependent killing by NATURAL KILLER CELLS and granulocytes. Intracellular adhesion molecule-1 has been defined as a ligand for lymphocyte function-associated antigen-1.

Broader concept

Related concepts

Entry terms

  • Integrin alphaLbeta2
  • Leukocyte Function Associated Antigen-1
  • LFA-1

Allowable Qualifier(s)

In other languages

  • Antigène-1 associé à la fonction du lymphocyte

    French

  • Antigène LFA-1
  • Antigène-1 associé à la fonction des leucocytes
  • Antigène-1 associé à la fonction des lymphocytes
  • Antigène-1 associé à la fonction du leucocyte
  • Antigène-1 associé à la fonction leucocytaire
  • Antigène-1 associé à la fonction lymphocytaire
  • Intégrine alpha-L-bêta-2
  • Intégrine alphaLbêta2
  • LFA-1(Lymphocyte function-associated antigen-1)

URI

http://data.loterre.fr/ark:/67375/JVR-PHX28MJC-K

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RDF/XML TURTLE JSON-LD Created 4/24/90, last modified 7/13/17