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Concept information

Preferred term

Myelinolysis, Central Pontine  

Type

  • mesh:Descriptor

Definition

  • A demyelinating condition affecting the PONS and characterized clinically by an acute progressive QUADRIPLEGIA; DYSARTHRIA; DYSPHAGIA; and alterations of consciousness. Pathologic features include prominent demyelination in the central PONS with sparing of axons and neurons. This condition is usually associated with systemic disorders such as HYPONATREMIA; chronic ALCOHOLISM; LIVER FAILURE; severe BURNS; malignant NEOPLASMS; hemorrhagic PANCREATITIS; HEMODIALYSIS; and SEPSIS. The rapid medical correction of hyponatremia has been cited as a cause of this condition. (From Adams et al., Principles of Neurology, 6th ed, pp1125-6)

Entry terms

  • Central Pontine Myelinolysis
  • Myelinoclasis, Central Pontine
  • Pontine Myelinolysis, Central

In other languages

  • French

  • Démyélinisation de la protubérance annulaire
  • Myélinolyse centrale du pont
  • Myélinolyse centrale du pont de Varole
  • Myélinolyse centro-pontine
  • Myélinolyse centro-pontique
  • Myélinolyse centropontique

URI

http://data.loterre.fr/ark:/67375/JVR-PJSN9GJQ-Q

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RDF/XML TURTLE JSON-LD Created 12/28/92, last modified 7/6/09