Concept information
Preferred term
Gabexate
Type
-
mesh:Descriptor
Definition
- A serine proteinase inhibitor used therapeutically in the treatment of pancreatitis, disseminated intravascular coagulation (DIC), and as a regional anticoagulant for hemodialysis. The drug inhibits the hydrolytic effects of thrombin, plasmin, and kallikrein, but not of chymotrypsin and aprotinin.
Broader concept
Entry terms
- 102391-46-8 (methanesulfonate)
- 39492-01-8 (Gabexate)
- 4V7M9137X9
- 56974-48-2 (monomethanesulfonate(14C-labeled cpd))
- 56974-61-9 (monomethanesulfonate)
- Benzoic acid, 4-((6-((aminoiminomethyl)amino)-1-oxohexyl)oxy)-, ethyl ester
- E3Q07L0649
Allowable Qualifier(s)
- administration & dosage (Qualifier)
- adverse effects (Qualifier)
- agonists (Qualifier)
- analogs & derivatives (Qualifier)
- analysis (Qualifier)
- antagonists & inhibitors (Qualifier)
- blood (Qualifier)
- cerebrospinal fluid (Qualifier)
- chemical synthesis (Qualifier)
- chemistry (Qualifier)
- classification (Qualifier)
- economics (Qualifier)
- history (Qualifier)
- immunology (Qualifier)
- isolation & purification (Qualifier)
- metabolism (Qualifier)
- pharmacokinetics (Qualifier)
- pharmacology (Qualifier)
- poisoning (Qualifier)
- radiation effects (Qualifier)
- standards (Qualifier)
- supply & distribution (Qualifier)
- therapeutic use (Qualifier)
- toxicity (Qualifier)
- urine (Qualifier)
Pharmacological Action(s)
In other languages
-
French
-
102391-46-8 (methanesulfonate)
-
39492-01-8 (Gabexate)
-
4V7M9137X9
-
56974-48-2 (monomethanesulfonate(14C-labeled cpd))
-
56974-61-9 (monomethanesulfonate)
-
Benzoic acid, 4-((6-((aminoiminomethyl)amino)-1-oxohexyl)oxy)-, ethyl ester
-
E3Q07L0649
URI
http://data.loterre.fr/ark:/67375/JVR-PS4CT10W-Q
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