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... > Enzymes and Coenzymes > Enzymes > Ligases > Ubiquitin-Protein Ligase Complexes > Ubiquitin-Protein Ligases > Polycomb Repressive Complex 1
Macromolecular Substances > Multiprotein Complexes > Polycomb-Group Proteins > Polycomb Repressive Complex 1
... > Amino Acids, Peptides, and Proteins > Proteins > DNA-Binding Proteins > Repressor Proteins > Polycomb-Group Proteins > Polycomb Repressive Complex 1
... > Amino Acids, Peptides, and Proteins > Proteins > Transcription Factors > Repressor Proteins > Polycomb-Group Proteins > Polycomb Repressive Complex 1
... > Amino Acids, Peptides, and Proteins > Proteins > Nucleoproteins > Chromosomal Proteins, Non-Histone > Polycomb-Group Proteins > Polycomb Repressive Complex 1
... > Amino Acids, Peptides, and Proteins > Proteins > Nuclear Proteins > Chromosomal Proteins, Non-Histone > Polycomb-Group Proteins > Polycomb Repressive Complex 1

Preferred term

Polycomb Repressive Complex 1  

Type

  • mesh:Descriptor

Definition

  • A multisubunit polycomb protein complex with affinity for CHROMATIN that contains methylated HISTONE H3. It contains an E3 ubiquitin ligase activity that is specific for HISTONE H2A and works in conjunction with POLYCOMB REPRESSIVE COMPLEX 2 to effect EPIGENETIC REPRESSION.

Broader concept

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URI

http://data.loterre.fr/ark:/67375/JVR-PS7JLQPW-M

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RDF/XML TURTLE JSON-LD Created 7/3/12, last modified 6/2/16