Concept information
Amino Acids, Peptides, and Proteins
Peptides
Intracellular Signaling Peptides and Proteins
Adaptor Proteins, Signal Transducing
Preferred term
Interferon-Stimulated Gene Factor 3
Type
-
mesh:Descriptor
Definition
- A multimeric complex that functions as a ligand-dependent transcription factor. ISGF3 is assembled in the CYTOPLASM and translocated to the CELL NUCLEUS in response to INTERFERON signaling. It consists of ISGF3-GAMMA and ISGF3-ALPHA, and it regulates expression of many interferon-responsive GENES.
Narrower concepts
Entry terms
- IFN-Stimulated Gene Factor 3 Complex
- ISGF3 Factor
- ISGF3 Transcription Factor
- Transcription Factor ISGF3
Allowable Qualifier(s)
- administration & dosage (Qualifier)
- adverse effects (Qualifier)
- agonists (Qualifier)
- analysis (Qualifier)
- antagonists & inhibitors (Qualifier)
- biosynthesis (Qualifier)
- blood (Qualifier)
- cerebrospinal fluid (Qualifier)
- chemical synthesis (Qualifier)
- chemistry (Qualifier)
- classification (Qualifier)
- deficiency (Qualifier)
- drug effects (Qualifier)
- economics (Qualifier)
- genetics (Qualifier)
- history (Qualifier)
- immunology (Qualifier)
- isolation & purification (Qualifier)
- metabolism (Qualifier)
- pharmacokinetics (Qualifier)
- pharmacology (Qualifier)
- physiology (Qualifier)
- poisoning (Qualifier)
- radiation effects (Qualifier)
- standards (Qualifier)
- supply & distribution (Qualifier)
- therapeutic use (Qualifier)
- toxicity (Qualifier)
- ultrastructure (Qualifier)
- urine (Qualifier)
In other languages
-
French
-
Complexe ISGF-3
-
Complexe transcriptionnel ISGF3
-
Facteur de transcription ISGF-3
-
Facteur de transcription ISGF3
-
Facteur ISGF3
-
Facteur transcriptionnel ISGF3
-
Protéine ISG-F-3
-
Protéine ISGF-3
URI
http://data.loterre.fr/ark:/67375/JVR-PTQZ8WPS-G
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