Concept information
Preferred term
Core Binding Factor alpha Subunits
Type
-
mesh:Descriptor
Definition
- A family of transcription factors that bind to the cofactor CORE BINDING FACTOR BETA SUBUNIT to form core binding factor. Family members contain a highly conserved DNA-binding domain known as the runt domain. They can act as both activators and repressors of expression of GENES involved in CELL DIFFERENTIATION and CELL CYCLE progression.
Broader concept
Narrower concepts
Entry terms
- Acute Myeloid Leukemia Proteins
- Core Binding Factor alpha Proteins
- PEBP2A Transcription Factors
- Polyomavirus Enhancer A Binding Protein 2
- Polyomavirus Enhancer Binding Protein 2, Alpha Subunit
- Runt Domain Factor
- Runx Proteins
Allowable Qualifier(s)
- administration & dosage (Qualifier)
- adverse effects (Qualifier)
- agonists (Qualifier)
- analysis (Qualifier)
- antagonists & inhibitors (Qualifier)
- biosynthesis (Qualifier)
- blood (Qualifier)
- cerebrospinal fluid (Qualifier)
- chemical synthesis (Qualifier)
- chemistry (Qualifier)
- classification (Qualifier)
- deficiency (Qualifier)
- drug effects (Qualifier)
- economics (Qualifier)
- genetics (Qualifier)
- history (Qualifier)
- immunology (Qualifier)
- isolation & purification (Qualifier)
- metabolism (Qualifier)
- pharmacokinetics (Qualifier)
- pharmacology (Qualifier)
- physiology (Qualifier)
- poisoning (Qualifier)
- radiation effects (Qualifier)
- standards (Qualifier)
- supply & distribution (Qualifier)
- therapeutic use (Qualifier)
- toxicity (Qualifier)
- ultrastructure (Qualifier)
- urine (Qualifier)
In other languages
-
French
-
Acute myeloid leukemia proteins
-
Core binding factor alpha subunits
-
Facteur de transcription à domaine Runt
-
Facteurs de transcription AML
-
Facteurs de transcription CBF-alpha
-
Facteurs de transcription CBF/AML
-
Facteurs de transcription PEBP2A
-
Polyomavirus enhancer A binding protein 2
-
Polyomavirus enhancer binding protein 2 alpha subunit
-
Protéines AML
-
Protéines CBF-alpha
-
Protéines Runx
URI
http://data.loterre.fr/ark:/67375/JVR-Q4LZ57KX-B
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