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Amino Acids, Peptides, and Proteins > Peptides > Intracellular Signaling Peptides and Proteins > Apoptosis Regulatory Proteins > Inhibitor of Apoptosis Proteins
Amino Acids, Peptides, and Proteins > Proteins > Intracellular Signaling Peptides and Proteins > Apoptosis Regulatory Proteins > Inhibitor of Apoptosis Proteins
... > Enzymes and Coenzymes > Enzymes > Ligases > Ubiquitin-Protein Ligase Complexes > Ubiquitin-Protein Ligases > Inhibitor of Apoptosis Proteins

Preferred term

Inhibitor of Apoptosis Proteins  

Type

  • mesh:Descriptor

Definition

  • A conserved class of proteins that control APOPTOSIS in both VERTEBRATES and INVERTEBRATES. IAP proteins interact with and inhibit CASPASES, and they function as ANTI-APOPTOTIC PROTEINS. The protein class is defined by an approximately 80-amino acid motif called the baculoviral inhibitor of apoptosis repeat; some members have ubiquitin-protein ligase activity.

Broader concept

Narrower concepts

Entry terms

  • Baculoviral Inhibitor Of Apoptosis Repeat Proteins
  • IAP Protein (Apoptosis)
  • IAP Repeat Containing Proteins
  • Inhibitor-Of-Apoptosis Protein

Allowable Qualifier(s)

Pharmacological Action(s)

In other languages

  • Protéines IAP

    French

  • Protéine de type IAP
  • Protéines à domaine BIR (Baculovirus Inhibitory Repeat)
  • Protéines de type IAP
  • Protéines inhibitrices de l'apoptose

URI

http://data.loterre.fr/ark:/67375/JVR-Q5F0LWJ9-W

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RDF/XML TURTLE JSON-LD Created 6/30/05, last modified 6/29/17