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Biological Factors > Intercellular Signaling Peptides and Proteins > Cytokines > Transforming Growth Factor beta > Transforming Growth Factor beta2
... > Amino Acids, Peptides, and Proteins > Peptides > Intercellular Signaling Peptides and Proteins > Cytokines > Transforming Growth Factor beta > Transforming Growth Factor beta2
... > Amino Acids, Peptides, and Proteins > Proteins > Intercellular Signaling Peptides and Proteins > Cytokines > Transforming Growth Factor beta > Transforming Growth Factor beta2
Biological Factors > Intercellular Signaling Peptides and Proteins > TGF-beta Superfamily Proteins > Transforming Growth Factor beta > Transforming Growth Factor beta2
... > Amino Acids, Peptides, and Proteins > Peptides > Intercellular Signaling Peptides and Proteins > TGF-beta Superfamily Proteins > Transforming Growth Factor beta > Transforming Growth Factor beta2
... > Amino Acids, Peptides, and Proteins > Proteins > Intercellular Signaling Peptides and Proteins > TGF-beta Superfamily Proteins > Transforming Growth Factor beta > Transforming Growth Factor beta2

Preferred term

Transforming Growth Factor beta2  

Type

  • mesh:Descriptor

Definition

  • A TGF-beta subtype that was originally identified as a GLIOBLASTOMA-derived factor which inhibits the antigen-dependent growth of both helper and CYTOTOXIC T LYMPHOCYTES. It is synthesized as a precursor molecule that is cleaved to form mature TGF-beta2 and TGF-beta2 latency-associated peptide. The association of the cleavage products results in the formation a latent protein which must be activated to bind its receptor.

Broader concept

Entry terms

  • BSC-1 Cell Growth Inhibitor
  • Cartilage-Inducing Factor-B
  • Glioblastoma-Derived T-Cell Suppressor Factor
  • Polyergin
  • Suppressor Factor, T-Cell, Glioblastoma-Derived
  • TGF-beta-2
  • TGF-beta2

Allowable Qualifier(s)

In other languages

URI

http://data.loterre.fr/ark:/67375/JVR-Q74J99MD-N

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RDF/XML TURTLE JSON-LD Created 7/5/06, last modified 6/2/15