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Concept information

Preferred term

CADASIL  

Type

  • mesh:Descriptor

Definition

  • A familial, cerebral arteriopathy mapped to chromosome 19q12, and characterized by the presence of granular deposits in small CEREBRAL ARTERIES producing ischemic STROKE; PSEUDOBULBAR PALSY; and multiple subcortical infarcts (CEREBRAL INFARCTION). CADASIL is an acronym for Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy. CADASIL differs from BINSWANGER DISEASE by the presence of MIGRAINE WITH AURA and usually by the lack of history of arterial HYPERTENSION. (From Bradley et al, Neurology in Clinical Practice, 2000, p1146) A subvariety of CADASIL characterized by the high frequency of MIGRAINE. The acronym stands for Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts, Leukoencephalopathy, and Migraine.

Entry terms

  • Cerebral Arteriopathy with Subcortical Infarcts and Leukoencephalopathy
  • Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy
  • Dementia, Hereditary Multi-Infarct Type

In other languages

  • French

  • Démence-infarctus cérébraux multiples héréditaires

URI

http://data.loterre.fr/ark:/67375/JVR-Q8W7HLTJ-3

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RDF/XML TURTLE JSON-LD Created 7/7/04, last modified 7/1/19