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Concept information

Preferred term

NF-kappa B p50 Subunit  

Type

  • mesh:Descriptor

Definition

  • A component of NF-kappa B transcription factor. It is proteolytically processed from NF-kappa B p105 precursor protein and is capable of forming dimeric complexes with itself or with TRANSCRIPTION FACTOR RELA. It regulates expression of GENES involved in immune and inflammatory responses. NF-kappa B p105 precursor protein is constitutively processed by the PROTEASOME to produce NF-kappa B p50 subunit. It helps regulate map kinase signaling through its association with Map3k8 protein.

Broader concept

Entry terms

  • NF-kappaB 50-kDa
  • NF-kappa B p50
  • NFKB1 Transcription Factor

In other languages

  • French

  • Facteur de transcription NF-kappaB1
  • Facteur de transcription NFKB-1
  • Facteur de transcription NFKB1
  • Facteur transcriptionnel NFKB1
  • NF-kappa B p50
  • NF-kappa B-1
  • NF-kappaB 50-kDa
  • NF-kappaB1
  • Sous-unité NF-kappa B p50
  • Sous-unité p50 du facteur de transcription NF-kappa B

URI

http://data.loterre.fr/ark:/67375/JVR-QDW9QMZW-V

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RDF/XML TURTLE JSON-LD Created 6/30/05, last modified 7/19/05