Concept information
Preferred term
NF-kappa B p50 Subunit
Type
-
mesh:Descriptor
Definition
- A component of NF-kappa B transcription factor. It is proteolytically processed from NF-kappa B p105 precursor protein and is capable of forming dimeric complexes with itself or with TRANSCRIPTION FACTOR RELA. It regulates expression of GENES involved in immune and inflammatory responses. NF-kappa B p105 precursor protein is constitutively processed by the PROTEASOME to produce NF-kappa B p50 subunit. It helps regulate map kinase signaling through its association with Map3k8 protein.
Broader concept
Entry terms
- NF-kappaB 50-kDa
- NF-kappa B p50
- NFKB1 Transcription Factor
Allowable Qualifier(s)
- administration & dosage (Qualifier)
- adverse effects (Qualifier)
- agonists (Qualifier)
- analysis (Qualifier)
- antagonists & inhibitors (Qualifier)
- biosynthesis (Qualifier)
- blood (Qualifier)
- cerebrospinal fluid (Qualifier)
- chemical synthesis (Qualifier)
- chemistry (Qualifier)
- classification (Qualifier)
- deficiency (Qualifier)
- drug effects (Qualifier)
- economics (Qualifier)
- genetics (Qualifier)
- history (Qualifier)
- immunology (Qualifier)
- isolation & purification (Qualifier)
- metabolism (Qualifier)
- pharmacokinetics (Qualifier)
- pharmacology (Qualifier)
- physiology (Qualifier)
- poisoning (Qualifier)
- radiation effects (Qualifier)
- standards (Qualifier)
- supply & distribution (Qualifier)
- therapeutic use (Qualifier)
- toxicity (Qualifier)
- ultrastructure (Qualifier)
- urine (Qualifier)
In other languages
-
French
-
Facteur de transcription NF-kappaB1
-
Facteur de transcription NFKB-1
-
Facteur de transcription NFKB1
-
Facteur transcriptionnel NFKB1
-
NF-kappa B p50
-
NF-kappa B-1
-
NF-kappaB 50-kDa
-
NF-kappaB1
-
Sous-unité NF-kappa B p50
-
Sous-unité p50 du facteur de transcription NF-kappa B
URI
http://data.loterre.fr/ark:/67375/JVR-QDW9QMZW-V
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