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Concept information

Preferred term

Endothelin-1  

Type

  • mesh:Descriptor

Definition

  • A 21-amino acid peptide produced in a variety of tissues including endothelial and vascular smooth-muscle cells, neurons and astrocytes in the central nervous system, and endometrial cells. It acts as a modulator of vasomotor tone, cell proliferation, and hormone production. (N Eng J Med 1995;333(6):356-63) A 38 amino acid form of endothelin-1 that results from alternative processing of proendothelin-1.

Broader concept

Entry terms

  • 114540-95-3
  • 122462-75-3
  • Endothelin Type 1

In other languages

URI

http://data.loterre.fr/ark:/67375/JVR-QG2Z5VJK-1

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RDF/XML TURTLE JSON-LD Created 6/10/96, last modified 6/26/15