Concept information
Preferred term
Swainsonine
Type
-
mesh:Descriptor
Definition
- An indolizidine alkaloid from the plant Swainsona canescens that is a potent alpha-mannosidase inhibitor. Swainsonine also exhibits antimetastatic, antiproliferative, and immunomodulatory activity.
Broader concept
Entry terms
- 107982-28-5 ((1R-(2 beta,8a alpha))-isomer)
- 111467-60-8 ((8a alpha)-isomer)
- 116497-15-5 ((2 beta,8a alpha)-isomer)
- 116497-16-6 ((8 alpha,8a alpha)-isomer)
- 1,2,8-Indolizinetriol, octahydro-, (1S-(1alpha,2alpha,8beta,8abeta))-
- 72741-87-8 (Swainsonine)
- 96648-51-0 ((8 alpha)-isomer)
- RSY4RK37KQ
Allowable Qualifier(s)
- administration & dosage (Qualifier)
- adverse effects (Qualifier)
- agonists (Qualifier)
- analogs & derivatives (Qualifier)
- analysis (Qualifier)
- antagonists & inhibitors (Qualifier)
- blood (Qualifier)
- cerebrospinal fluid (Qualifier)
- chemical synthesis (Qualifier)
- chemistry (Qualifier)
- classification (Qualifier)
- economics (Qualifier)
- history (Qualifier)
- immunology (Qualifier)
- isolation & purification (Qualifier)
- metabolism (Qualifier)
- pharmacokinetics (Qualifier)
- pharmacology (Qualifier)
- poisoning (Qualifier)
- radiation effects (Qualifier)
- standards (Qualifier)
- supply & distribution (Qualifier)
- therapeutic use (Qualifier)
- toxicity (Qualifier)
- urine (Qualifier)
Pharmacological Action(s)
In other languages
-
French
-
1,2,8-Indolizinetriol, octahydro-, (1S-(1alpha,2alpha,8beta,8abeta))-
-
107982-28-5 ((1R-(2 beta,8a alpha))-isomer)
-
111467-60-8 ((8a alpha)-isomer)
-
116497-15-5 ((2 beta,8a alpha)-isomer)
-
116497-16-6 ((8 alpha,8a alpha)-isomer)
-
72741-87-8 (Swainsonine)
-
96648-51-0 ((8 alpha)-isomer)
-
RSY4RK37KQ
-
Swainsonine
URI
http://data.loterre.fr/ark:/67375/JVR-QG80Z6S1-C
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