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... > Amino Acids, Peptides, and Proteins > Proteins > Membrane Proteins > Membrane Transport Proteins > Ion Pumps > Cation Transport Proteins > Organic Cation Transport Proteins > Solute Carrier Family 22 Member 5
... > Amino Acids, Peptides, and Proteins > Proteins > Carrier Proteins > Membrane Transport Proteins > Ion Pumps > Cation Transport Proteins > Organic Cation Transport Proteins > Solute Carrier Family 22 Member 5
... > Amino Acids, Peptides, and Proteins > Proteins > Membrane Proteins > Membrane Transport Proteins > Solute Carrier Proteins > Organic Cation Transport Proteins > Solute Carrier Family 22 Member 5
... > Amino Acids, Peptides, and Proteins > Proteins > Carrier Proteins > Membrane Transport Proteins > Solute Carrier Proteins > Organic Cation Transport Proteins > Solute Carrier Family 22 Member 5

Preferred term

Solute Carrier Family 22 Member 5  

Type

  • mesh:Descriptor

Definition

  • A high-affinity, ATP-binding, co-transporter for CARNITINE that is highly expressed in kidney, skeletal muscle, heart, and placental tissues. It transports one sodium ion with one carnitine molecule. It has a lower affinity for other organic cations and transports them independently of sodium. Mutations in the SLC22A5 gene are associated with systemic carnitine deficiency.

Broader concept

Entry terms

  • High-Affinity Carnitine Transporter
  • OCTN2 Protein
  • Organic Cation-Carnitine Transporter 2
  • SLC22A5 Protein
  • Sodium-Dependent Carnitine Cotransporter

Allowable Qualifier(s)

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URI

http://data.loterre.fr/ark:/67375/JVR-QNHQPXHD-9

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RDF/XML TURTLE JSON-LD Created 7/11/17, last modified 3/31/17