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Concept information

Preferred term

Paraneoplastic Cerebellar Degeneration  

Type

  • mesh:Descriptor

Definition

  • Cerebellar degeneration associated with a remote neoplasm. Clinical manifestations include progressive limb and GAIT ATAXIA; DYSARTHRIA; and NYSTAGMUS, PATHOLOGIC. The histologic type of the associated neoplasm is usually carcinoma or lymphoma. Pathologically the cerebellar cortex and subcortical nuclei demonstrate diffuse degenerative changes. Anti-Purkinje cell antibodies (anti-Yo) are found in the serum of approximately 50% of affected individuals. (Adams et al., Principles of Neurology, 6th ed, p686)

Entry terms

  • Cerebellar Degeneration, Paraneoplastic
  • Cerebellar Syndrome, Paraneoplastic
  • Paraneoplastic Cerebellar Syndrome

URI

http://data.loterre.fr/ark:/67375/JVR-QNQHRQ57-J

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RDF/XML TURTLE JSON-LD Created 11/4/99, last modified 7/6/09