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Concept information

... > Lipids > Fatty Acids > Fatty Acids, Unsaturated > Eicosanoids > Prostaglandins > Prostaglandins, Synthetic > Prostaglandins E, Synthetic > Rioprostil
... > Biological Factors > Inflammation Mediators > Autacoids > Eicosanoids > Prostaglandins > Prostaglandins, Synthetic > Prostaglandins E, Synthetic > Rioprostil

Preferred term

Rioprostil  

Type

  • mesh:Descriptor

Definition

  • A synthetic methylprostaglandin E1 analog that reduces gastric acid secretion and enhances the gastric mucus-bicarbonate barrier. It is effective in the therapy of gastric ulcers and gives significant protection against NSAID-induced gastric mucosal damage. The drug also prevents cyclosporin A-induced damage to endocrine and exocrine pancreatic secretions. It shows a low order of acute toxicity and there is no evidence of embryotoxicity, fetotoxicity, teratogenicity, or mutagenicity in animal studies.

Broader concept

Entry terms

  • 77287-05-9 (Rioprostil)
  • 7JL402PVQR
  • Prost-13-en-9-one, 1,11,16-trihydroxy-16-methyl-, (11alpha,13E)-

Allowable Qualifier(s)

Pharmacological Action(s)

In other languages

  • Rioprostil

    French

  • 77287-05-9 (Rioprostil)
  • 7JL402PVQR
  • Prost-13-en-9-one, 1,11,16-trihydroxy-16-methyl-, (11alpha,13E)-

URI

http://data.loterre.fr/ark:/67375/JVR-QQGJDZVV-J

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