Concept information
Preferred term
Decitabine
Type
-
mesh:Descriptor
Definition
- An azacitidine derivative and antineoplastic antimetabolite. It inhibits DNA methyltransferase to re-activate silent genes, limiting METASTASIS and NEOPLASM DRUG RESISTANCE. Decitabine is used in the treatment of MYELODISPLASTIC SYNDROMES, and ACUTE MYELOID LEUKEMIA.
Broader concept
Entry terms
- 2353-33-5 (Decitabine)
- 2'-Deoxy-5-azacytidine
- 5-Aza-2'-deoxycytidine
- 5-AzadC
- 5AzadC
- 5-Azadeoxycytidine
- 6U3LPL9PRN
- 776B62CQ27
- AzadC Compound
Allowable Qualifier(s)
- administration & dosage (Qualifier)
- adverse effects (Qualifier)
- agonists (Qualifier)
- analogs & derivatives (Qualifier)
- analysis (Qualifier)
- antagonists & inhibitors (Qualifier)
- blood (Qualifier)
- cerebrospinal fluid (Qualifier)
- chemical synthesis (Qualifier)
- chemistry (Qualifier)
- classification (Qualifier)
- economics (Qualifier)
- history (Qualifier)
- immunology (Qualifier)
- isolation & purification (Qualifier)
- metabolism (Qualifier)
- pharmacokinetics (Qualifier)
- pharmacology (Qualifier)
- poisoning (Qualifier)
- radiation effects (Qualifier)
- standards (Qualifier)
- supply & distribution (Qualifier)
- therapeutic use (Qualifier)
- toxicity (Qualifier)
- urine (Qualifier)
Pharmacological Action(s)
In other languages
-
French
-
2353-33-5 (Decitabine)
-
6U3LPL9PRN
-
776B62CQ27
URI
http://data.loterre.fr/ark:/67375/JVR-QW5X8DBR-Z
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