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Concept information

Preferred term

Spleen Focus-Forming Viruses  

Type

  • mesh:Descriptor

Definition

  • Strains of MURINE LEUKEMIA VIRUS that are replication-defective and rapidly transforming. The envelope gene plays an essential role in initiating erythroleukemia (LEUKEMIA, ERYTHROBLASTIC, ACUTE), manifested by splenic foci, SPLENOMEGALY, and POLYCYTHEMIA. Spleen focus-forming viruses are generated by recombination with endogenous retroviral sequences.

Broader concept

Entry terms

  • SFFV
  • txid11819
  • txid11820
  • txid11821

In other languages

URI

http://data.loterre.fr/ark:/67375/JVR-QXJGLFJW-L

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RDF/XML TURTLE JSON-LD Created 5/9/85, last modified 8/13/20