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Amino Acids, Peptides, and Proteins > Proteins > Nerve Tissue Proteins > Microtubule-Associated Proteins > tau Proteins
... > Amino Acids, Peptides, and Proteins > Proteins > Cytoskeletal Proteins > Microtubule Proteins > Microtubule-Associated Proteins > tau Proteins
... > Technology, Industry, and Agriculture > Manufactured Materials > Biomedical and Dental Materials > Polymers > Biopolymers > Microtubule Proteins > Microtubule-Associated Proteins > tau Proteins
... > Chemical Actions and Uses > Specialty Uses of Chemicals > Biomedical and Dental Materials > Polymers > Biopolymers > Microtubule Proteins > Microtubule-Associated Proteins > tau Proteins
... > Macromolecular Substances > Polymers > Biopolymers > Microtubule Proteins > Microtubule-Associated Proteins > tau Proteins

Preferred term

tau Proteins  

Type

  • mesh:Descriptor

Definition

  • Microtubule-associated proteins that are mainly expressed in neurons. Tau proteins constitute several isoforms and play an important role in the assembly of tubulin monomers into microtubules and in maintaining the cytoskeleton and axonal transport. Aggregation of specific sets of tau proteins in filamentous inclusions is the common feature of intraneuronal and glial fibrillar lesions (NEUROFIBRILLARY TANGLES; NEUROPIL THREADS) in numerous neurodegenerative disorders (ALZHEIMER DISEASE; TAUOPATHIES).

Broader concept

Related concepts

Entry terms

  • tau Protein

Allowable Qualifier(s)

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URI

http://data.loterre.fr/ark:/67375/JVR-R096N43X-R

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RDF/XML TURTLE JSON-LD Created 7/12/91, last modified 7/5/16