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Amino Acids, Peptides, and Proteins > Peptides > Intracellular Signaling Peptides and Proteins > Adaptor Proteins, Signal Transducing > mTOR Associated Protein, LST8 Homolog
Amino Acids, Peptides, and Proteins > Proteins > Intracellular Signaling Peptides and Proteins > Adaptor Proteins, Signal Transducing > mTOR Associated Protein, LST8 Homolog
Amino Acids, Peptides, and Proteins > Proteins > Carrier Proteins > Adaptor Proteins, Signal Transducing > mTOR Associated Protein, LST8 Homolog
Macromolecular Substances > Multiprotein Complexes > Mechanistic Target of Rapamycin Complex 1 > mTOR Associated Protein, LST8 Homolog
... > Amino Acids, Peptides, and Proteins > Peptides > Intracellular Signaling Peptides and Proteins > Protein Serine-Threonine Kinases > TOR Serine-Threonine Kinases > Mechanistic Target of Rapamycin Complex 1 > mTOR Associated Protein, LST8 Homolog
... > Amino Acids, Peptides, and Proteins > Proteins > Intracellular Signaling Peptides and Proteins > Protein Serine-Threonine Kinases > TOR Serine-Threonine Kinases > Mechanistic Target of Rapamycin Complex 1 > mTOR Associated Protein, LST8 Homolog
... > Enzymes and Coenzymes > Enzymes > Transferases > Phosphotransferases > Phosphotransferases (Alcohol Group Acceptor) > Protein Kinases > Protein Serine-Threonine Kinases > TOR Serine-Threonine Kinases > Mechanistic Target of Rapamycin Complex 1 > mTOR Associated Protein, LST8 Homolog

Preferred term

mTOR Associated Protein, LST8 Homolog  

Type

  • mesh:Descriptor

Definition

  • An adaptor protein, consisting of seven WD REPEATS along its length, that functions as a component of the MECHANISTIC TARGET OF RAPAMYCIN COMPLEX 1 and mTORC2 COMPLEX. It interacts directly with mTOR to enhance its kinase activity and stabilizes the mTOR-RPTOR PROTEIN interaction in nutrient-poor conditions, favoring RPTOR inhibition of mTOR activity.

Broader concept

Entry terms

  • GBetaL Protein
  • G protein beta Subunit-like Polypeptide
  • mLST8 Protein

Allowable Qualifier(s)

In other languages

URI

http://data.loterre.fr/ark:/67375/JVR-R0CL2W05-B

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RDF/XML TURTLE JSON-LD Created 7/11/17, last modified 5/21/21