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Concept information

Preferred term

Hemoglobinuria, Paroxysmal  

Type

  • mesh:Descriptor

Definition

  • A condition characterized by the recurrence of HEMOGLOBINURIA caused by intravascular HEMOLYSIS. In cases occurring upon cold exposure (paroxysmal cold hemoglobinuria), usually after infections, there is a circulating antibody which is also a cold hemolysin. In cases occurring during or after sleep (paroxysmal nocturnal hemoglobinuria), the clonal hematopoietic stem cells exhibit a global deficiency of cell membrane proteins.

Entry terms

  • Paroxysmal Hemoglobinuria

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URI

http://data.loterre.fr/ark:/67375/JVR-R2442SSX-1

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