Concept information
Preferred term
T-Lymphocytes, Cytotoxic
Type
-
mesh:Descriptor
Definition
- Immunized T-lymphocytes which can directly destroy appropriate target cells. These cytotoxic lymphocytes may be generated in vitro in mixed lymphocyte cultures (MLC), in vivo during a graft-versus-host (GVH) reaction, or after immunization with an allograft, tumor cell or virally transformed or chemically modified target cell. The lytic phenomenon is sometimes referred to as cell-mediated lympholysis (CML). These CD8-positive cells are distinct from NATURAL KILLER CELLS and NATURAL KILLER T-CELLS. There are two effector phenotypes: TC1 and TC2.
Entry terms
- Cell-Mediated Lympholytic Cells
- Cytotoxic T Lymphocyte
- Cytotoxic T-Lymphocytes
Allowable Qualifier(s)
- chemistry (Qualifier)
- classification (Qualifier)
- cytology (Qualifier)
- drug effects (Qualifier)
- enzymology (Qualifier)
- immunology (Qualifier)
- metabolism (Qualifier)
- microbiology (Qualifier)
- parasitology (Qualifier)
- pathology (Qualifier)
- physiology (Qualifier)
- radiation effects (Qualifier)
- transplantation (Qualifier)
- ultrastructure (Qualifier)
- virology (Qualifier)
In other languages
-
French
-
Cellules CTL
-
Cellules T cytotoxiques
-
Cellules Tc
-
Lymphocyte T cytotoxique
-
Lymphocytes cytotoxiques T8
-
Lymphocytes Tc
-
Lymphocytes TCD8+ cytotoxiques
-
Lymphocytes Tcytotoxiques
URI
http://data.loterre.fr/ark:/67375/JVR-R4G3D97C-6
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