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Concept information

Cells > Cells, Cultured > Cytokine-Induced Killer Cells > T-Lymphocytes, Cytotoxic

Preferred term

T-Lymphocytes, Cytotoxic  

Type

  • mesh:Descriptor

Definition

  • Immunized T-lymphocytes which can directly destroy appropriate target cells. These cytotoxic lymphocytes may be generated in vitro in mixed lymphocyte cultures (MLC), in vivo during a graft-versus-host (GVH) reaction, or after immunization with an allograft, tumor cell or virally transformed or chemically modified target cell. The lytic phenomenon is sometimes referred to as cell-mediated lympholysis (CML). These CD8-positive cells are distinct from NATURAL KILLER CELLS and NATURAL KILLER T-CELLS. There are two effector phenotypes: TC1 and TC2.

Entry terms

  • Cell-Mediated Lympholytic Cells
  • Cytotoxic T Lymphocyte
  • Cytotoxic T-Lymphocytes

In other languages

  • French

  • Cellules CTL
  • Cellules T cytotoxiques
  • Cellules Tc
  • Lymphocyte T cytotoxique
  • Lymphocytes cytotoxiques T8
  • Lymphocytes Tc
  • Lymphocytes TCD8+ cytotoxiques
  • Lymphocytes Tcytotoxiques

URI

http://data.loterre.fr/ark:/67375/JVR-R4G3D97C-6

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