Concept information
Preferred term
2-Acetylaminofluorene
Type
-
mesh:Descriptor
Definition
- A hepatic carcinogen whose mechanism of activation involves N-hydroxylation to the aryl hydroxamic acid followed by enzymatic sulfonation to sulfoxyfluorenylacetamide. It is used to study the carcinogenicity and mutagenicity of aromatic amines.
Broader concept
Narrower concepts
Entry terms
- 2-AAF
- 2-Acetamidofluorene
- 2-Fluorenylacetamide
- 53-96-3 (2-Acetylaminofluorene)
- 9M98QLJ2DL
- AAF, Aminofluorene
- Acetamide, N-9H-fluoren-2-yl-
- Fluoren-2-ylacetamide
- N-2-Fluorenylacetamide
- N-Acetyl-2-Aminofluorene
Allowable Qualifier(s)
- administration & dosage (Qualifier)
- adverse effects (Qualifier)
- agonists (Qualifier)
- analogs & derivatives (Qualifier)
- analysis (Qualifier)
- antagonists & inhibitors (Qualifier)
- blood (Qualifier)
- cerebrospinal fluid (Qualifier)
- chemical synthesis (Qualifier)
- chemistry (Qualifier)
- classification (Qualifier)
- economics (Qualifier)
- history (Qualifier)
- immunology (Qualifier)
- isolation & purification (Qualifier)
- metabolism (Qualifier)
- pharmacokinetics (Qualifier)
- pharmacology (Qualifier)
- poisoning (Qualifier)
- radiation effects (Qualifier)
- standards (Qualifier)
- supply & distribution (Qualifier)
- therapeutic use (Qualifier)
- toxicity (Qualifier)
- urine (Qualifier)
Pharmacological Action(s)
In other languages
-
French
-
53-96-3 (2-Acetylaminofluorene)
-
9M98QLJ2DL
-
Acetamide, N-9H-fluoren-2-yl-
-
N-Fluorén-2-ylacétamide
URI
http://data.loterre.fr/ark:/67375/JVR-R7DR7QTK-F
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