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Biological Factors > Intercellular Signaling Peptides and Proteins > Cytokines > Interleukins > Interleukin-12
... > Amino Acids, Peptides, and Proteins > Peptides > Intercellular Signaling Peptides and Proteins > Cytokines > Interleukins > Interleukin-12
... > Amino Acids, Peptides, and Proteins > Proteins > Intercellular Signaling Peptides and Proteins > Cytokines > Interleukins > Interleukin-12

Preferred term

Interleukin-12  

Type

  • mesh:Descriptor

Definition

  • A heterodimeric cytokine that plays a role in innate and adaptive immune responses. Interleukin-12 is a 70 kDa protein that is composed of covalently linked 40 kDa and 35 kDa subunits. It is produced by DENDRITIC CELLS; MACROPHAGES and a variety of other immune cells and plays a role in the stimulation of INTERFERON-GAMMA production by T-LYMPHOCYTES and NATURAL KILLER CELLS.

Broader concept

Narrower concepts

Related concepts

Entry terms

  • 187348-17-0
  • Cytotoxic Lymphocyte Maturation Factor
  • IL 12
  • IL-12
  • IL12
  • IL-12 p70
  • Interleukin 12
  • Interleukin-12 p70
  • Natural Killer Cell Stimulatory Factor

Allowable Qualifier(s)

Pharmacological Action(s)

In other languages

  • Interleukine-12

    French

  • 187348-17-0
  • Édodékine alfa
  • Facteur de maturation des lymphocytes cytotoxiques
  • Facteur de stimulation des cellules NK
  • Facteur de stimulation des cellules tueuses naturelles
  • IL-12
  • IL-12p70
  • IL12

URI

http://data.loterre.fr/ark:/67375/JVR-R7DX2K1F-L

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RDF/XML TURTLE JSON-LD Created 4/19/94, last modified 10/10/18