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Amino Acids, Peptides, and Proteins > Peptides > Intracellular Signaling Peptides and Proteins > Protein Serine-Threonine Kinases > Receptor, Transforming Growth Factor-beta Type II
Amino Acids, Peptides, and Proteins > Proteins > Intracellular Signaling Peptides and Proteins > Protein Serine-Threonine Kinases > Receptor, Transforming Growth Factor-beta Type II
... > Enzymes and Coenzymes > Enzymes > Transferases > Phosphotransferases > Phosphotransferases (Alcohol Group Acceptor) > Protein Kinases > Protein Serine-Threonine Kinases > Receptor, Transforming Growth Factor-beta Type II
... > Amino Acids, Peptides, and Proteins > Proteins > Membrane Proteins > Receptors, Cell Surface > Receptors, Peptide > Receptors, Growth Factor > Receptors, Transforming Growth Factor beta > Receptor, Transforming Growth Factor-beta Type II
... > Amino Acids, Peptides, and Proteins > Proteins > Membrane Proteins > Receptors, Cell Surface > Receptors, Immunologic > Receptors, Cytokine > Receptors, Transforming Growth Factor beta > Receptor, Transforming Growth Factor-beta Type II

Preferred term

Receptor, Transforming Growth Factor-beta Type II  

Type

  • mesh:Descriptor

Definition

  • A transmembrane serine-threonine kinase that forms a heteromeric complex with TYPE I TGF-BETA RECEPTORS when bound to TGF-BETA. This receptor complex regulates a variety of physiological and pathological processes including CELL CYCLE ARREST; CELL PROLIFERATION; CELL DIFFERENTIATION; WOUND HEALING; EXTRACELLULAR MATRIX production, immunosuppression and ONCOGENESIS.

Broader concept

Entry terms

  • TbetaR-II Kinase
  • TGF-beta Type II Receptor
  • TGF-beta Type II Receptors
  • TGFBR2
  • Transforming Growth Factor-beta Type II Receptor
  • Transforming Growth Factor-beta Type II Receptors
  • Type II TGF-beta Receptor
  • Type II TGF-beta Receptors

Allowable Qualifier(s)

In other languages

URI

http://data.loterre.fr/ark:/67375/JVR-RD76C4TZ-8

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RDF/XML TURTLE JSON-LD Created 7/9/18, last modified 5/21/21