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... > Amino Acids, Peptides, and Proteins > Proteins > Glycoproteins > Membrane Glycoproteins > ATP-Binding Cassette Transporters > ATP Binding Cassette Transporter, Subfamily B > ATP Binding Cassette Transporter, Subfamily B, Member 1
... > Carbohydrates > Glycoconjugates > Glycoproteins > Membrane Glycoproteins > ATP-Binding Cassette Transporters > ATP Binding Cassette Transporter, Subfamily B > ATP Binding Cassette Transporter, Subfamily B, Member 1
... > Amino Acids, Peptides, and Proteins > Proteins > Membrane Proteins > Membrane Glycoproteins > ATP-Binding Cassette Transporters > ATP Binding Cassette Transporter, Subfamily B > ATP Binding Cassette Transporter, Subfamily B, Member 1
... > Amino Acids, Peptides, and Proteins > Proteins > Membrane Proteins > Membrane Transport Proteins > ATP-Binding Cassette Transporters > ATP Binding Cassette Transporter, Subfamily B > ATP Binding Cassette Transporter, Subfamily B, Member 1
... > Amino Acids, Peptides, and Proteins > Proteins > Carrier Proteins > Membrane Transport Proteins > ATP-Binding Cassette Transporters > ATP Binding Cassette Transporter, Subfamily B > ATP Binding Cassette Transporter, Subfamily B, Member 1
... > Amino Acids, Peptides, and Proteins > Proteins > Membrane Proteins > Membrane Transport Proteins > Ion Pumps > Anion Transport Proteins > Organic Anion Transporters > Organic Anion Transporters, ATP-Dependent > ATP Binding Cassette Transporter, Subfamily B > ATP Binding Cassette Transporter, Subfamily B, Member 1
... > Amino Acids, Peptides, and Proteins > Proteins > Carrier Proteins > Membrane Transport Proteins > Ion Pumps > Anion Transport Proteins > Organic Anion Transporters > Organic Anion Transporters, ATP-Dependent > ATP Binding Cassette Transporter, Subfamily B > ATP Binding Cassette Transporter, Subfamily B, Member 1

Preferred term

ATP Binding Cassette Transporter, Subfamily B, Member 1  

Type

  • mesh:Descriptor

Definition

  • A 170-kDa transmembrane glycoprotein from the superfamily of ATP-BINDING CASSETTE TRANSPORTERS. It serves as an ATP-dependent efflux pump for a variety of chemicals, including many ANTINEOPLASTIC AGENTS. Overexpression of this glycoprotein is associated with multidrug resistance (see DRUG RESISTANCE, MULTIPLE).

Broader concept

Related concepts

Entry terms

  • ABCB1 Protein
  • ATP-Binding Cassette, Sub-Family B, Member 1
  • ATP Binding Cassette Transporter, Sub-Family B, Member 1
  • CD243 Antigen
  • MDR1 Protein
  • Multidrug Resistance Protein 1
  • P-Glycoprotein
  • PGY-1 Protein

Allowable Qualifier(s)

In other languages

URI

http://data.loterre.fr/ark:/67375/JVR-RDNJDZPW-L

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RDF/XML TURTLE JSON-LD Created 7/20/98, last modified 7/13/18