: MeSH: Hyperhomocysteinemia

... > Malnutrition > Deficiency Diseases > Avitaminosis > Vitamin B Deficiency > Hyperhomocysteinemia

Digestive System Diseases > Gastrointestinal Diseases > Intestinal Diseases > Malabsorption Syndromes > Hyperhomocysteinemia

Nutritional and Metabolic Diseases > Metabolic Diseases > Malabsorption Syndromes > Hyperhomocysteinemia

Congenital, Hereditary, and Neonatal Diseases and Abnormalities > Genetic Diseases, Inborn > Metabolism, Inborn Errors > Amino Acid Metabolism, Inborn Errors > Hyperhomocysteinemia

Nutritional and Metabolic Diseases > Metabolic Diseases > Metabolism, Inborn Errors > Amino Acid Metabolism, Inborn Errors > Hyperhomocysteinemia

Hyperhomocysteinemia

Condition in which the plasma levels of homocysteine and related metabolites are elevated (>13.9 μmol/l). Hyperhomocysteinemia can be familial or acquired. Development of the acquired hyperhomocysteinemia is mostly associated with vitamins B and/or folate deficiency (e.g., PERNICIOUS ANEMIA, vitamin malabsorption). Familial hyperhomocysteinemia often results in a more severe elevation of total homocysteine and excretion into the urine, resulting in HOMOCYSTINURIA. Hyperhomocysteinemia is a risk factor for cardiovascular and neurodegenerative diseases, osteoporotic fractures and complications during pregnancy.

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