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Amino Acids, Peptides, and Proteins > Proteins > Nerve Tissue Proteins > Neuropeptides > Pancreatic Polypeptide
Amino Acids, Peptides, and Proteins > Peptides > Neuropeptides > Pancreatic Polypeptide
Amino Acids, Peptides, and Proteins > Peptides > Peptide Hormones > Pancreatic Hormones > Pancreatic Polypeptide
... > Chemical Actions and Uses > Pharmacologic Actions > Physiological Effects of Drugs > Hormones, Hormone Substitutes, and Hormone Antagonists > Hormones > Peptide Hormones > Pancreatic Hormones > Pancreatic Polypeptide

Preferred term

Pancreatic Polypeptide  

Type

  • mesh:Descriptor

Definition

  • A 36-amino acid pancreatic hormone that is secreted mainly by endocrine cells found at the periphery of the ISLETS OF LANGERHANS and adjacent to cells containing SOMATOSTATIN and GLUCAGON. Pancreatic polypeptide (PP), when administered peripherally, can suppress gastric secretion, gastric emptying, pancreatic enzyme secretion, and appetite. A lack of pancreatic polypeptide (PP) has been associated with OBESITY in rats and mice. A secreted polypeptide of about 100 amino acids, depending on the species, from the PANCREASE. It is the precursor of pancreatic polypeptide (PP) and a pancreatic C-terminal peptide or pancreatic icosapeptide.

Broader concept

Entry terms

  • 59763-91-6
  • Pancreatic Polypeptide Hormone
  • Pancreatic Polypeptide (PP)

Allowable Qualifier(s)

Pharmacological Action(s)

In other languages

URI

http://data.loterre.fr/ark:/67375/JVR-RNMCZ5L8-M

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RDF/XML TURTLE JSON-LD Created 5/18/78, last modified 11/24/15