Concept information
Preferred term
Cytochrome P-450 CYP11B2
Type
-
mesh:Descriptor
Definition
- A mitochondrial cytochrome P450 enzyme that catalyzes the 18-hydroxylation of steroids in the presence of molecular oxygen and NADPH-specific flavoprotein. This enzyme, encoded by CYP11B2 gene, is important in the conversion of CORTICOSTERONE to 18-hydroxycorticosterone and the subsequent conversion to ALDOSTERONE.
Broader concept
Entry terms
- 37256-75-0 (CRN)
- Aldosterone Synthase
- Aldosterone Synthase Cytochrome P-450
- Aldosynthase
- CYP 11B2
- CYP11B2
- Cytochrome P450 11B2
- Cytochrome P450Aldo
- Cytochrome P-450c11AS
- P450c11AS
- Steroid 18-Hydroxylase
Allowable Qualifier(s)
- administration & dosage (Qualifier)
- adverse effects (Qualifier)
- analysis (Qualifier)
- antagonists & inhibitors (Qualifier)
- biosynthesis (Qualifier)
- blood (Qualifier)
- cerebrospinal fluid (Qualifier)
- chemical synthesis (Qualifier)
- chemistry (Qualifier)
- classification (Qualifier)
- deficiency (Qualifier)
- drug effects (Qualifier)
- economics (Qualifier)
- genetics (Qualifier)
- history (Qualifier)
- immunology (Qualifier)
- isolation & purification (Qualifier)
- metabolism (Qualifier)
- pharmacokinetics (Qualifier)
- pharmacology (Qualifier)
- physiology (Qualifier)
- poisoning (Qualifier)
- radiation effects (Qualifier)
- standards (Qualifier)
- supply & distribution (Qualifier)
- therapeutic use (Qualifier)
- toxicity (Qualifier)
- ultrastructure (Qualifier)
- urine (Qualifier)
In other languages
-
French
-
37256-75-0 (CRN)
-
Aldosterone synthase
-
Aldostérone synthase
-
Aldosterone synthase cytochrome P-450
-
Aldostérone synthétase
-
Aldosynthase
-
CYP 11B2
-
CYP11B2
-
Cytochrome P-450c11AS
-
Cytochrome P450 11B2
-
Cytochrome P450aldo
-
P450c11AS
-
Stéroïde 18-hydroxylase
URI
http://data.loterre.fr/ark:/67375/JVR-RP66FFN2-J
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