Concept information
Preferred term
Mice, Inbred MRL lpr
Type
-
mesh:Descriptor
Definition
- A mouse substrain that is genetically predisposed to the development of systemic lupus erythematosus-like syndrome, which has been found to be clinically similar to the human disease. It has been determined that this mouse strain carries a mutation in the fas gene. Also, the MRL/lpr is a useful model to study behavioral and cognitive deficits found in autoimmune diseases and the efficacy of immunosuppressive agents.
Broader concept
Entry terms
- Mice, MRL lpr
- Mouse, Inbred MRL lpr
- Mouse, MRL lpr
Allowable Qualifier(s)
- abnormalities (Qualifier)
- anatomy & histology (Qualifier)
- blood (Qualifier)
- cerebrospinal fluid (Qualifier)
- classification (Qualifier)
- embryology (Qualifier)
- genetics (Qualifier)
- growth & development (Qualifier)
- immunology (Qualifier)
- injuries (Qualifier)
- metabolism (Qualifier)
- microbiology (Qualifier)
- parasitology (Qualifier)
- physiology (Qualifier)
- psychology (Qualifier)
- surgery (Qualifier)
- urine (Qualifier)
- virology (Qualifier)
In other languages
-
French
-
Souris de souche MRL lpr
-
Souris MRL lpr
URI
http://data.loterre.fr/ark:/67375/JVR-RS4BP2M8-K
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