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Amino Acids, Peptides, and Proteins > Proteins > Glycoproteins > Complement C1 Inhibitor Protein
Carbohydrates > Glycoconjugates > Glycoproteins > Complement C1 Inhibitor Protein
... > Chemical Actions and Uses > Pharmacologic Actions > Molecular Mechanisms of Pharmacological Action > Enzyme Inhibitors > Protease Inhibitors > Serine Proteinase Inhibitors > Serpins > Complement C1 Inactivator Proteins > Complement C1 Inhibitor Protein
Amino Acids, Peptides, and Proteins > Peptides > Serpins > Complement C1 Inactivator Proteins > Complement C1 Inhibitor Protein
Amino Acids, Peptides, and Proteins > Proteins > Serpins > Complement C1 Inactivator Proteins > Complement C1 Inhibitor Protein
... > Amino Acids, Peptides, and Proteins > Proteins > Blood Proteins > Immunoproteins > Complement System Proteins > Complement Inactivator Proteins > Complement C1 Inactivator Proteins > Complement C1 Inhibitor Protein

Preferred term

Complement C1 Inhibitor Protein  

Type

  • mesh:Descriptor

Definition

  • An endogenous 105-kDa plasma glycoprotein produced primarily by the LIVER and MONOCYTES. It inhibits a broad spectrum of proteases, including the COMPLEMENT C1R and the COMPLEMENT C1S proteases of the CLASSICAL COMPLEMENT PATHWAY, and the MANNOSE-BINDING PROTEIN-ASSOCIATED SERINE PROTEASES. C1-INH-deficient individuals suffer from HEREDITARY ANGIOEDEMA TYPES I AND II.

Broader concept

Related concepts

Entry terms

  • C1 Esterase Inhibitor
  • C1-Inhibitor Protein
  • C1-INH Protein
  • Complement C1-Inhibitor Protein
  • Plasma Protease C1 Inhibitor
  • Serpin Family G Member 1
  • Serpin G1
  • SERPING1

Allowable Qualifier(s)

Pharmacological Action(s)

In other languages

  • C1 Inhibiteur

    French

  • C1 inh
  • Inhibiteur C1
  • Inhibiteur de la C1 estérase
  • Inhibiteur de la fraction C1 du complément
  • Inhibiteur du composant C1 du complément
  • Protéine C1-INH
  • Serpine G1

URI

http://data.loterre.fr/ark:/67375/JVR-RTF0P2JR-H

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RDF/XML TURTLE JSON-LD Created 6/30/05, last modified 3/4/21