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Concept information

... > Enzymes and Coenzymes > Enzymes > Hydrolases > Peptide Hydrolases > Proprotein Convertases > Carboxypeptidase B2
... > Enzymes and Coenzymes > Enzymes > Hydrolases > Peptide Hydrolases > Exopeptidases > Metalloexopeptidases > Carboxypeptidase B2
... > Enzymes and Coenzymes > Enzymes > Hydrolases > Peptide Hydrolases > Metalloproteases > Metalloexopeptidases > Carboxypeptidase B2
... > Enzymes and Coenzymes > Enzymes > Hydrolases > Peptide Hydrolases > Exopeptidases > Carboxypeptidases > Carboxypeptidase B2

Preferred term

Carboxypeptidase B2  

Type

  • mesh:Descriptor

Definition

  • A carboxypeptidase that removes C-terminal lysine or arginine from peptides and proteins. Carboxypeptidase B2 (CPB2) is released into the circulation as a proenzyme which is activated by the THROMBIN-THROMBOMODULIN complex. Activated CPB2 is involved in modulating a variety of processes by cleaving and inactivating various circulating proteins and peptides that are its substrates including FIBRIN; KININS; and ANAPHYLATOXINS.

Broader concept

Entry terms

  • Arginine Carboxypeptidase
  • Carboxypeptidase B2, Plasma
  • Carboxypeptidase R
  • Carboxypeptidase U
  • Thrombin-Activatable Fibrinolysis Inhibitor
  • Thrombin-Activatable Fibrinolysis Inhibitor (TAFI)

Allowable Qualifier(s)

In other languages

  • Carboxypeptidase B2

    French

  • Arginine carboxypeptidase
  • Carboxypeptidase B2 du plasma
  • Carboxypeptidase R
  • Carboxypeptidase U
  • Inhibiteur de la fibrinolyse activable par la thrombine
  • TAFI
  • Thrombin-activatable fibrinolysis inhibitor

URI

http://data.loterre.fr/ark:/67375/JVR-RVW4PM5D-D

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RDF/XML TURTLE JSON-LD Created 7/25/01, last modified 6/6/14