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... > Amino Acids, Peptides, and Proteins > Proteins > Membrane Proteins > Receptors, Cell Surface > Receptors, Collagen > Integrin alpha2beta1
... > Amino Acids, Peptides, and Proteins > Proteins > Membrane Proteins > Receptors, Cell Surface > Receptors, Immunologic > Platelet Membrane Glycoproteins > Integrin alpha2beta1
... > Amino Acids, Peptides, and Proteins > Proteins > Glycoproteins > Membrane Glycoproteins > Platelet Membrane Glycoproteins > Integrin alpha2beta1
... > Carbohydrates > Glycoconjugates > Glycoproteins > Membrane Glycoproteins > Platelet Membrane Glycoproteins > Integrin alpha2beta1
... > Amino Acids, Peptides, and Proteins > Proteins > Membrane Proteins > Membrane Glycoproteins > Platelet Membrane Glycoproteins > Integrin alpha2beta1
... > Amino Acids, Peptides, and Proteins > Proteins > Membrane Proteins > Receptors, Cell Surface > Receptors, Immunologic > Receptors, Laminin > Integrin alpha2beta1
... > Amino Acids, Peptides, and Proteins > Proteins > Membrane Proteins > Receptors, Cell Surface > Receptors, Immunologic > Integrins > Receptors, Very Late Antigen > Integrin alpha2beta1
... > Amino Acids, Peptides, and Proteins > Proteins > Membrane Proteins > Receptors, Cell Surface > Receptors, Immunologic > Integrins > Receptors, Fibronectin > Integrin alpha2beta1

Preferred term

Integrin alpha2beta1  

Type

  • mesh:Descriptor

Definition

  • An integrin found on fibroblasts, platelets, endothelial and epithelial cells, and lymphocytes where it functions as a receptor for COLLAGEN and LAMININ. Although originally referred to as the collagen receptor, it is one of several receptors for collagen. Ligand binding to integrin alpha2beta1 triggers a cascade of intracellular signaling, including activation of p38 MAP kinase.

Broader concept

Entry terms

  • alpha2beta1Integrin
  • CD49b-CD29
  • Glycoprotein Ia-IIa
  • Platelet Membrane Glycoprotein Heterodimer Ia-IIa
  • Very Late Antigen-2
  • VLA-2

Allowable Qualifier(s)

In other languages

  • Intégrine alpha2bêta1

    French

  • Antigène-2 de l'activation très tardive
  • CD49b-CD29
  • Intégrine alpha-2-bêta-1
  • Intégrine alpha2 bêta1
  • VLA-2

URI

http://data.loterre.fr/ark:/67375/JVR-RZR9MB17-G

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RDF/XML TURTLE JSON-LD Created 7/2/02, last modified 6/17/16