Concept information
Preferred term
Oncogenes
Type
-
mesh:Descriptor
Definition
- Genes whose gain-of-function alterations lead to NEOPLASTIC CELL TRANSFORMATION. They include, for example, genes for activators or stimulators of CELL PROLIFERATION such as growth factors, growth factor receptors, protein kinases, signal transducers, nuclear phosphoproteins, and transcription factors. A prefix of "v-" before oncogene symbols indicates oncogenes captured and transmitted by RETROVIRUSES; the prefix "c-" before the gene symbol of an oncogene indicates it is the cellular homolog (PROTO-ONCOGENES) of a v-oncogene.
Broader concept
Narrower concepts
Entry terms
- Oncogene
- Transforming Gene
- Transforming Genes
Allowable Qualifier(s)
In other languages
-
French
-
Gènes transformants
-
Oncogène
URI
http://data.loterre.fr/ark:/67375/JVR-S1L8LZQ9-2
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