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Concept information

Preferred term

Stevens-Johnson Syndrome  

Type

  • mesh:Descriptor

Definition

  • Rare cutaneous eruption characterized by extensive KERATINOCYTE apoptosis resulting in skin detachment with mucosal involvement. It is often provoked by the use of drugs (e.g., antibiotics and anticonvulsants) or associated with PNEUMONIA, MYCOPLASMA. It is considered a continuum of Toxic Epidermal Necrolysis. An exfoliative disease of skin seen primarily in adults and characterized by flaccid bullae and spreading erythema so that the skin has the appearance of being scalded. It results primarily from a toxic reaction to various drugs, but occasionally occurs as a result of infection, neoplastic conditions, or other exposure.

In other languages

  • French

  • Dermatostomatite
  • Ectodermose érosive pluri-orificielle
  • SSJ (Syndrome de Stevens-Johnson)
  • Syndrome de Baader
  • Syndrome de Fiessinger-Rendu

URI

http://data.loterre.fr/ark:/67375/JVR-S1Q3HJNC-R

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