Concept information
Preferred term
Receptors, Death Domain
Type
-
mesh:Descriptor
Definition
- A family of cell surface receptors that signal via a conserved domain that extends into the cell CYTOPLASM. The conserved domain is referred to as a DEATH DOMAIN due to the fact that many of these receptors are involved in APOPTOSIS signaling pathways. Several DEATH DOMAIN RECEPTOR SIGNALING ADAPTOR PROTEINS can bind to the death domains of the activated receptors and through a complex series of interactions activate apoptotic mediators such as CASPASES.
Broader concept
Narrower concepts
Entry terms
- Death Domain Receptors
- Death Receptor
- Death Receptors
- Receptors, Death Domain Family
- Receptors, DR Family
Allowable Qualifier(s)
- administration & dosage (Qualifier)
- agonists (Qualifier)
- analysis (Qualifier)
- antagonists & inhibitors (Qualifier)
- biosynthesis (Qualifier)
- blood (Qualifier)
- chemistry (Qualifier)
- classification (Qualifier)
- deficiency (Qualifier)
- drug effects (Qualifier)
- genetics (Qualifier)
- history (Qualifier)
- immunology (Qualifier)
- isolation & purification (Qualifier)
- metabolism (Qualifier)
- physiology (Qualifier)
- radiation effects (Qualifier)
- therapeutic use (Qualifier)
- ultrastructure (Qualifier)
In other languages
-
French
-
Famille des récepteurs à domaine de mort
-
Récepteurs de mort
URI
http://data.loterre.fr/ark:/67375/JVR-S331W3FM-M
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