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Concept information

Amino Acids, Peptides, and Proteins > Amino Acids > Amino Acids, Dicarboxylic > Glutamates > Pemetrexed
Amino Acids, Peptides, and Proteins > Amino Acids > Amino Acids, Acidic > Glutamates > Pemetrexed
... > Heterocyclic Compounds > Heterocyclic Compounds, Fused-Ring > Heterocyclic Compounds, 2-Ring > Purines > Purinones > Hypoxanthines > Guanine > Pemetrexed

Preferred term

Pemetrexed  

Type

  • mesh:Descriptor

Definition

  • A guanine-derived ANTINEOPLASTIC AGENT that functions as a NUCLEIC ACID SYNTHESIS INHIBITOR through its binding to, and inhibition of, THYMIDYLATE SYNTHASE.

Broader concept

Entry terms

  • 04Q9AIZ7NO
  • 137281-23-3 (pemetrexed)
  • 2PKU919BA9
  • L-Glutamic acid, N-(4-(2-(2-amino-4,7-dihydro-4-oxo-1H-pyrrolo(2,3-d)pyrimidin-5-yl)ethyl)benzoyl)-
  • MTA
  • N-(4-(2-(2-amino-3,4-dihydro-4-oxo-7H-pyrrolo(2,3-d)pyrimdin-5-yl)ethyl)benzoyl)glutamic acid

Allowable Qualifier(s)

Pharmacological Action(s)

In other languages

  • Pémétrexed

    French

  • 04Q9AIZ7NO
  • 137281-23-3 (pemetrexed)
  • 2PKU919BA9
  • L-Glutamic acid, N-(4-(2-(2-amino-4,7-dihydro-4-oxo-1H-pyrrolo(2,3-d)pyrimidin-5-yl)ethyl)benzoyl)-

URI

http://data.loterre.fr/ark:/67375/JVR-S3PM6SKJ-N

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RDF/XML TURTLE JSON-LD Created 7/1/15, last modified 5/31/16