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Nervous System Diseases > Autoimmune Diseases of the Nervous System > Myasthenia Gravis > Myasthenia Gravis, Autoimmune, Experimental

Preferred term

Myasthenia Gravis, Autoimmune, Experimental  

Type

  • mesh:Descriptor

Definition

  • Any autoimmune animal disease model used in the study of MYASTHENIA GRAVIS. Injection with purified neuromuscular junction acetylcholine receptor (AChR) (see RECEPTORS, CHOLINERGIC) components results in a myasthenic syndrome that has acute and chronic phases. The motor endplate pathology, loss of acetylcholine receptors, presence of circulating anti-AChR antibodies, and electrophysiologic changes make this condition virtually identical to human myasthenia gravis. Passive transfer of AChR antibodies or lymphocytes from afflicted animals to normals induces passive transfer experimental autoimmune myasthenia gravis. (From Joynt, Clinical Neurology, 1997, Ch 54, p3)

Entry terms

  • Autoimmune Experimental Myasthenia Gravis
  • Experimental Myasthenia
  • Experimental Myasthenia Gravis
  • Myasthenia Gravis, Autoimmune Experimental
  • Myasthenia Gravis, Experimental Autoimmune

In other languages

  • French

  • MAE (Myasthénie Auto-immune Expérimentale)
  • Myasthenia gravis autoimmune expérimentale
  • Myasthénie allergique expérimentale
  • Myasthénie autoimmune expérimentale
  • Myasthénie expérimentale

URI

http://data.loterre.fr/ark:/67375/JVR-S51JD3MV-B

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