Concept information
Amino Acids, Peptides, and Proteins
Peptides
Intracellular Signaling Peptides and Proteins
3',5'-Cyclic-AMP Phosphodiesterases
Preferred term
Cyclic Nucleotide Phosphodiesterases, Type 4
Type
-
mesh:Descriptor
Definition
- A cyclic nucleotide phosphodiesterase subfamily that is found predominantly in inflammatory cells and may play a role in the regulation of CELL-MEDIATED IMMUNITY. The enzyme family includes over twenty different variants that occur due to multiple ALTERNATIVE SPLICING of the mRNA of at least four different genes.
Broader concept
Entry terms
- Cyclic Nucleotide Phosphodiesterase PDE4 Family
- PDE4 Phosphodiesterases
- Phosphodiesterase 4
- Phosphodiesterase-4
- Phosphodiesterase IV
- Type 4 Cyclic Nucleotide Phosphodiesterase
Allowable Qualifier(s)
- administration & dosage (Qualifier)
- adverse effects (Qualifier)
- analysis (Qualifier)
- biosynthesis (Qualifier)
- blood (Qualifier)
- cerebrospinal fluid (Qualifier)
- chemical synthesis (Qualifier)
- chemistry (Qualifier)
- classification (Qualifier)
- deficiency (Qualifier)
- drug effects (Qualifier)
- economics (Qualifier)
- genetics (Qualifier)
- history (Qualifier)
- immunology (Qualifier)
- isolation & purification (Qualifier)
- metabolism (Qualifier)
- pharmacokinetics (Qualifier)
- pharmacology (Qualifier)
- physiology (Qualifier)
- poisoning (Qualifier)
- radiation effects (Qualifier)
- standards (Qualifier)
- supply & distribution (Qualifier)
- therapeutic use (Qualifier)
- toxicity (Qualifier)
- ultrastructure (Qualifier)
- urine (Qualifier)
In other languages
-
French
-
PDE de type 4
-
Phosphodiestérase IV
-
Phosphodiestérase-4
-
Phosphodiestérases des nucléotides cycliques de type 4
-
Phosphodiestérases des nucléotides cycliques de type IV
-
Phosphodiestérases PDE4
URI
http://data.loterre.fr/ark:/67375/JVR-S74F0P1J-3
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