Concept information
Preferred term
Cytochrome P-450 CYP2B1
Type
-
mesh:Descriptor
Definition
- A major cytochrome P-450 enzyme which is inducible by PHENOBARBITAL in both the LIVER and SMALL INTESTINE. It is active in the metabolism of compounds like pentoxyresorufin, TESTOSTERONE, and ANDROSTENEDIONE. This enzyme, encoded by CYP2B1 gene, also mediates the activation of CYCLOPHOSPHAMIDE and IFOSFAMIDE to MUTAGENS.
Broader concept
Entry terms
- 7-Benzyloxyresorufin O-Dealkylase
- 7-Pentylresorufin O-Depentylase
- Benzyloxyresorufin O-Dealkylase
- BROD
- CYP 2B1
- CYP2B1
- Cytochrome P450 2B1
- Pentoxyresorufin O-Dealkylase
- PROD
Allowable Qualifier(s)
- administration & dosage (Qualifier)
- adverse effects (Qualifier)
- analysis (Qualifier)
- antagonists & inhibitors (Qualifier)
- biosynthesis (Qualifier)
- blood (Qualifier)
- cerebrospinal fluid (Qualifier)
- chemical synthesis (Qualifier)
- chemistry (Qualifier)
- classification (Qualifier)
- deficiency (Qualifier)
- drug effects (Qualifier)
- economics (Qualifier)
- genetics (Qualifier)
- history (Qualifier)
- immunology (Qualifier)
- isolation & purification (Qualifier)
- metabolism (Qualifier)
- pharmacokinetics (Qualifier)
- pharmacology (Qualifier)
- physiology (Qualifier)
- poisoning (Qualifier)
- radiation effects (Qualifier)
- standards (Qualifier)
- supply & distribution (Qualifier)
- therapeutic use (Qualifier)
- toxicity (Qualifier)
- ultrastructure (Qualifier)
- urine (Qualifier)
In other languages
-
French
-
Benzyloxyrésorufine O-désalkylase
-
BROD
-
CYP 2B1
-
CYP2B1
-
Cytochrome P450 2B1
-
Pentoxyrésorufine O-désalkylase
-
PROD
URI
http://data.loterre.fr/ark:/67375/JVR-S817MB3N-K
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