Concept information
Preferred term
Genes, abl
Type
-
mesh:Descriptor
Definition
- Retrovirus-associated DNA sequences (abl) originally isolated from the Abelson murine leukemia virus (Ab-MuLV). The proto-oncogene abl (c-abl) codes for a protein that is a member of the tyrosine kinase family. The human c-abl gene is located at 9q34.1 on the long arm of chromosome 9. It is activated by translocation to bcr on chromosome 22 in chronic myelogenous leukemia.
Broader concept
Entry terms
- abl Genes
Allowable Qualifier(s)
In other languages
-
French
-
Gène abl
URI
http://data.loterre.fr/ark:/67375/JVR-SFT9Z5SB-G
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