Concept information
Preferred term
Erythromycin Ethylsuccinate
Type
-
mesh:Descriptor
Definition
- A macrolide antibiotic, produced by Streptomyces erythreus. This compound is an ester of erythromycin base and succinic acid. It acts primarily as a bacteriostatic agent. In sensitive organisms, it inhibits protein synthesis by binding to 50S ribosomal subunits. This binding process inhibits peptidyl transferase activity and interferes with translocation of amino acids during translation and assembly of proteins.
Broader concept
Entry terms
- 1014KSJ86F
- 1264-62-6 (Erythromycin Ethylsuccinate)
- Erythromycin, 2'-(ethyl butanedioate)
- Eyrthromycin Ethyl Succinate
Allowable Qualifier(s)
- administration & dosage (Qualifier)
- adverse effects (Qualifier)
- agonists (Qualifier)
- analogs & derivatives (Qualifier)
- analysis (Qualifier)
- antagonists & inhibitors (Qualifier)
- biosynthesis (Qualifier)
- blood (Qualifier)
- cerebrospinal fluid (Qualifier)
- chemical synthesis (Qualifier)
- chemistry (Qualifier)
- classification (Qualifier)
- economics (Qualifier)
- history (Qualifier)
- immunology (Qualifier)
- isolation & purification (Qualifier)
- metabolism (Qualifier)
- pharmacokinetics (Qualifier)
- pharmacology (Qualifier)
- poisoning (Qualifier)
- radiation effects (Qualifier)
- standards (Qualifier)
- supply & distribution (Qualifier)
- therapeutic use (Qualifier)
- toxicity (Qualifier)
- urine (Qualifier)
Pharmacological Action(s)
In other languages
-
French
-
1014KSJ86F
-
1264-62-6 (Erythromycin Ethylsuccinate)
-
Erythromycin, 2'-(ethyl butanedioate)
-
Éthyl-succinate d'érythromycine
URI
http://data.loterre.fr/ark:/67375/JVR-SR9N97FK-C
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