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Concept information

Preferred term

Chondrodysplasia Punctata, Rhizomelic  

Type

  • mesh:Descriptor

Definition

  • An autosomal recessive form of CHONDRODYSPLASIA PUNCTATA characterized by defective plasmalogen biosynthesis and impaired peroxisomes. Patients have shortened proximal limbs and severely disturbed endochondral bone formation. The metabolic defects associated with the impaired peroxisomes are present only in the rhizomelic form of chondrodysplasia punctata. (From Scriver et al, Metabolic Basis of Inherited Disease, 6th ed, p1497)

Entry terms

  • Chondrodysplasia Punctata, Rhizomelic Form
  • Rhizomelic Chondrodysplasia Punctata

In other languages

URI

http://data.loterre.fr/ark:/67375/JVR-SST3MBRR-Z

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RDF/XML TURTLE JSON-LD Created 12/27/94, last modified 6/8/15