Concept information
Preferred term
Trefoil Factors
Type
-
mesh:Descriptor
Definition
- A family of small peptides expressed primarily by MUCOUS MEMBRANE EPITHELIAL CELLS in vertebrates. Their structure is highly conserved and is defined by a three-leaved (trefoil) domain of 42 or 43 amino acids; it includes six cysteines that create the trefoil structure through disulfide bridges. Trefoil peptides may form dimers with each other, or associate with MUCINS and other factors. They are important for maintaining epithelial integrity and for protection from noxious agents.
Broader concept
Narrower concepts
Entry terms
- TFF Peptide
- TFF Peptides
- Trefoil Factor
- Trefoil Factor Family Peptides
- Trefoil Factor Family Proteins
- Trefoil Peptide
- Trefoil Peptides
- Trefoil Protein
- Trefoil Proteins
Allowable Qualifier(s)
- administration & dosage (Qualifier)
- adverse effects (Qualifier)
- agonists (Qualifier)
- analogs & derivatives (Qualifier)
- analysis (Qualifier)
- antagonists & inhibitors (Qualifier)
- biosynthesis (Qualifier)
- blood (Qualifier)
- cerebrospinal fluid (Qualifier)
- chemical synthesis (Qualifier)
- chemistry (Qualifier)
- classification (Qualifier)
- deficiency (Qualifier)
- drug effects (Qualifier)
- economics (Qualifier)
- genetics (Qualifier)
- history (Qualifier)
- immunology (Qualifier)
- isolation & purification (Qualifier)
- metabolism (Qualifier)
- pharmacokinetics (Qualifier)
- pharmacology (Qualifier)
- physiology (Qualifier)
- poisoning (Qualifier)
- radiation effects (Qualifier)
- standards (Qualifier)
- supply & distribution (Qualifier)
- therapeutic use (Qualifier)
- toxicity (Qualifier)
- urine (Qualifier)
In other languages
-
French
-
Facteurs en feuille de trèfle
-
Peptides de la famille des facteurs en trèfle
-
Peptides en trèfle
-
Peptides TFF
-
Protéines de la famille des facteurs en trèfle
-
Protéines en trèfle
URI
http://data.loterre.fr/ark:/67375/JVR-SZSFNCVB-4
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