Concept information
Preferred term
Genes, erbB
Type
-
mesh:Descriptor
Definition
- Retrovirus-associated DNA sequences (erbB) originally isolated from, or related to, the avian erythroblastosis virus (AEV). These genes code for the epidermal growth factor receptor (EGFR) family of receptors which is important in the control of normal cell proliferation and in the pathogenesis of human cancer. The genes include erbB-1 (GENES, ERBB-1), erbB-2 (GENES, ERBB-2), and erbB-3, all of which show abnormalities of expression in various human neoplasms.
Broader concept
Narrower concepts
Entry terms
- erbB Genes
Allowable Qualifier(s)
In other languages
-
French
-
Gène erbB
URI
http://data.loterre.fr/ark:/67375/JVR-T7FSDK76-F
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