Concept information
Preferred term
Fluorouracil
Type
-
mesh:Descriptor
Definition
- A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
Broader concept
Narrower concepts
Entry terms
- 10318-20-4 (mono-Na salt)
- 2,4(1H,3H)-Pyrimidinedione, 5-fluoro-
- 51-21-8 (Fluorouracil)
- 57050-04-1 (K salt)
- 57172-36-8 (mononitrate)
- 5-Fluorouracil
- 5-FU
- 5FU
- 68021-61-4 (mono-K salt)
- Fluoruracil
- U3P01618RT
Allowable Qualifier(s)
- administration & dosage (Qualifier)
- adverse effects (Qualifier)
- agonists (Qualifier)
- analogs & derivatives (Qualifier)
- analysis (Qualifier)
- antagonists & inhibitors (Qualifier)
- blood (Qualifier)
- cerebrospinal fluid (Qualifier)
- chemical synthesis (Qualifier)
- chemistry (Qualifier)
- classification (Qualifier)
- economics (Qualifier)
- history (Qualifier)
- immunology (Qualifier)
- isolation & purification (Qualifier)
- metabolism (Qualifier)
- pharmacokinetics (Qualifier)
- pharmacology (Qualifier)
- poisoning (Qualifier)
- radiation effects (Qualifier)
- standards (Qualifier)
- supply & distribution (Qualifier)
- therapeutic use (Qualifier)
- toxicity (Qualifier)
- urine (Qualifier)
Pharmacological Action(s)
In other languages
-
French
-
10318-20-4 (mono-Na salt)
-
2,4(1H,3H)-Pyrimidinedione, 5-fluoro-
-
5-Fluoro-uracile
-
5-Fluorouracile
-
51-21-8 (Fluorouracil)
-
57050-04-1 (K salt)
-
57172-36-8 (mononitrate)
-
68021-61-4 (mono-K salt)
-
Fluorouracile
-
U3P01618RT
URI
http://data.loterre.fr/ark:/67375/JVR-T9GT2NB7-P
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